Ione's Lynx-N3 mouse has a built-in memory card reader. It connects to your PC via USB and needs no additional software to operate. Pointing performance is reasonable, with no evidence of the erratic movement common in cheaper devices. Its large body supports your hand well, but it's not comfortable to use with a card inserted. All standard card types are supported but the USB connection is not Hi-Speed, so transfer rates are limited to 1MB/s.
If you need a new mouse and a memory card reader the Lynx-N3 isn't the best example of either, but it does kill two birds with one inexpensive lump of plastic.